Basic purposes and principles
There are many different types of brain implant used today; the
simplest is a passive stimulator, like those used in deep brain
and vagus nerve stimulation, which simply applies pulses to a group
of neurons... more sophisticated stimulators can affect many distinct
neurons, as in cochlear implants. Highly refined arrays of micro-electrodes
allow transduction of useful sensory data into brain regions that
can receive and interpret them. Arrays of electrodes can also be
made to monitor neural activity, providing electrical outputs to
the neural system.
As increasingly sophisticated electrical devices are integrated
with neural tissues, an effective interface becomes highly significant.
Where arrays are interacting with hundreds or thousands of neurons
there must be a logical codec by which information can be exchanged
meaningfully. Devices that receive and integrate inputs from the
body often require tuning to an individual's specifications, as
well as to the type of information being exchanged. The study of
these neural correlates is termed neuro-informatics.
As is obvious from the language being used in this section, the
concept of data or information is merging with ideas of functional
brain activity. It makes sense that the wealth of knowledge on handling
and manipulating data, information in all its forms, would provide
useful handles for getting to grips with the flow of changes that
is brain activity. While useful, computational models of brain function
are not perfect, and should be seen as a stepping stone to deeper
understanding.
[Andersen et al,2004]
Cochlear implants
People who have suffered loss of the hairs that normally detect
vibrations in the ear can benefit by bypassing the hairs entirely
and stimulating the neurons directly. A device
using around 22 electrodes is implanted into the cochlea, which
receives a radio signal from a nearby processing unit. This unit
picks up sound though a microphone and analyses it before transmitting
to the implant. By using band-pass filters the sound is split into
frequency bands, similar to the ears natural way of differentiating
frequency. Modern implants also contain processors that emphasise
crucial vowel and consonant sounds to improve the users reception.
Effective use requires substantial tuning, where an audiologist
adjusts the device to suit the users needs. See a picture
[Litovsky et al,2004]
There is some controversy over the use of cochlear implants, especially
in young children, where parents are encouraged to pay for the expensive
operation to 'cure' their deaf child. Opponents are often deaf themselves
or closely associated with deaf people. They describe such treatment
as a brutal form of clinical eugenics, which is totally unnecessary,
as shown by the ability of deaf people to live happy and free lives
without any implants. Such debates are likely to continue, and even
escalate as more kinds of implant become available.
[Hazell, 1994]
Sensory substitution
Pioneered for people who aren't able to experience a sense, where
information is translated so as to be accessible by one of the functioning
senses. One example is of a tactile-visual substitution where a
camera translates optical input into pressure, sent to an array
of solenoids that are placed on the body. Similar systems exist
that translate images into sound, scanning from side to side, where
volume is brightness and pitch is position vertically. Naturally
a direct interface with the brain would allow greater throughput
and adaptability. The key to such implants working is plasticity
in the brain, as it must adapt to use the new incoming stimuli.
Thus the young are most able to such devices, although perhaps the
expanding knowledge of neurotrophins will make them accessible to
elders too.
[Hanneton et al,1999]
Deep brain stimulation
An increasingly common treatment for movement disorders, being
applied to other realms in recent years. See the DBS
page for a detailed discussion.
Retinal implants
It is possible to create visual artifacts in humans using stimulation
of the retina or visual cortex, using electrodes or trans-cranial
magnetic stimulation. These artifacts are usually just flashes,
but recently steps have been made to provide useful input to these
areas.
Pioneering work has used tiny implants to stimulate the retina in
partially sighted people. The implant consists of around 5000 tiny
photo-diodes that convert light into electricity, just as retinal
rods and cones do. Whole artificial retinas are also being tested,
and results appear positive. Future developments may allow external
modification of the signals produced by the implant, allowing vision
of 'virtual light' - images formed by external cameras or computers
could be viewed without a screen.
[Chow et al,2004]