Conclusion

Summing up this project:

It has been questioned whether pyrethroids interact competitively, as has been shown in vitro at high doses [Song et al, 1996; Motomura et al, 2001]. As people are frequently exposed to two or more pyrethroids, regulations on safe limits of exposure must take into this into account. Therefore one must know how pyrethroids are likely to interact within an organism to accurately calculate the risk for multiple-compound exposure.

The data suggested that the interaction between Esbiolethrin and Deltamethrin at doses 1.5x the LD50 in conscious rats was neither strongly additive, nor strongly competitive, appearing somewhere in the middle. One could stretch the imagination and see a slight trend towards competition; esbiolethrin may have been exerting a small antagonistic effect when applied with deltamethrin. However nobody is going to be giving esbiolethrin to cure deltamethrin poisoning any time soon. Pesticide manufacturers will probably be glad that no clear additive effect was observed as that would have surely left a bureaucrat fly in their economic soup.

Last words

......I hope you found this web site interesting, informative and well structured. Next time you see a chrysanthemum, you'll remember they are more than just beautiful flowers!

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